I will not in good conscience continue to give my three previously healthy dogs anymore Simparica Trio as it causing Gand Mal seizures in my older dog and nausea , vomiting and severe thirst and dehydration. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications. Work closely with and stay in touch with your vet (or even a board-certified veterinary dermatologist) to keep flares and other skin problems to a minimum. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. Free Shipping by Amazon . He is a 6 month old Bloodhound so they are always hyper. Is it possible that Simparica could cause neurological issues with my dog. It has been 20 days since I gave her the prescribed dose of Simparica. I am sure simparica caused a fatal seizure in my boxer. A skin disease such as a yeast infection or impetigo could also be the cause of your dog scratching all of the time. Seizures are going on two hours....☹️. IMPORTANT SAFETY INFORMATION Simparica is for use only in dogs 6 months of age and older. Wilkerson MJ et al. - 1800PetMeds. Consider allergen immunotherapy—either injections under the skin or allergy drops given orally to normalize your dog’s immune response to allergens. She falls when she runs and when going up and down stairs. Reading your comments, this drug may be the cause. He is eating fine with no diarrhea or vomiting. Furious that this out there for pets. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. Yeast infections could be a secondary infection to something such as an allergy. He already has canine dementia on and off. A week after my trek to the Mosquito Forest, there were no insects in sight. When I bathe him the scabs fall off and I think, oh good, this problem is going away. That evening after giving it to him he has puked various times. As fleas begin to die they will start to move around erratically as they start to lose their coordination, resulting in a transient increase in scratching behavior of your dog. I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. We gave our 3.5 month old Aussie pup a dose of Simparica today (vet's prescription), and I did not see the warnings about giving it to dogs under 6 months. The Maltese mix is lethargic and won’t jump on bed or couch. I give my dogs Simparica at the beginning of each month. I hate giving her these drugs in the first place but am always convinced it is the right thing to do. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. Then they come back! They have increased and worsened over the last 3 months. Gave my 14 month old 88 lb. My aunt gave her 5.5-kg, 13-year-old female shih tzu the first dose of Simparica and she has never been the same as she shows symptoms of cardiopulmonary illness: lethargy, loss of appetite, vomit, coughing, seizure and excessive drinking. If the tablet is not taken up voluntarily by the dog it can also be given with food or directly into the mouth. She had a second one hours later. We rushed him to the emergency vet and they put him on keppra to stop the seizures. This drug has caused our dog to loose his footing and not eat. Then she started having tremors. Your browser has JavaScript disabled, please turn it on in your browser settings. The scratching is likely because of the flea bites and not because of new live fleas on her. After a FUL neuro work up showed nothing abnormal, she was sent home on phenobarbital, but she is not experiencing twitching. I suppose with any drug, during trials, there will be some who have side effects ranging from negligible to life threatening. SIMPARICA is a flavored, chewable tablet for administration to dogs over 6 months of age according to their weight. Hi Laura, just wondering what supplements you gave your pup to help and how long it took for her to get back to herself after simparica. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. Refused to eat the rice and sweet potato I made for him last night. I am continuing to recover at home and have to use an oxygen tank. Not known if there be permanent after-effects. I threw him his ball and he actually was interested in it. (315 dogs treated with SIMPARICA and 164 dogs treated with active control once monthly for three treatments). My vet never mentioned that puppies under 6months cannot be prescribed this medication. If most side effects are mild, ( vomiting 12 hours later could be due to other things the dog has eaten within those 12 hours), I am ok with that. My veterinarian did not warn me of these and now my precious boxer is gone!!!!! My vet prescribed my 16 week old puppy this drug because of a skin irritation. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hours—including the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. gave this to my dog three different times. Second opinion] About 10 hours after receiving Simparica, my dog had her first grand mal seizure. The company that makes it said they didn’t change the flavor, but I live in a high tick area, so switched to Simparica Trio. Never happened before. We have an appt for a skin scraping. Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. We wont be using this medicine ever again! The most common adverse reactions in clinical trials were vomiting and diarrhea. Like many of you, I was unsure about the cause. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrhea—both symptoms related to Fido’s digestive tract, rather than his nervous system. It starts killing fleas after 3 hours and kills all fleas in 8 hours. After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. I will not give it to my puppy again, but what is a safer med. I have my 14 week old pup simparica (vet recommended) 2 days ago. It's normal for dogs to experience skin irritation at some point. Hours after receiving Simparica, my dog had her first grand meal seizure. Her heartbeat was more of a vibration than a beat and the vet wanted her to see a cardiologist. If your dog has a persistent itch that makes them scratch or chew themselves, a visit to your veterinarian will help narrow down the cause and get them started on a safe and effective anti-itch medication. Please advise! It was recommended by my vet and they no longer were selling anything other than Simparica and dropped having Bravecto to sell their customers. Every good pet parent wants to keep fleas off his dog, but many worries about the side effects that can accompany various flea and tick treatments. They could either keep her there for observation or I could take her home to observe her. Amazing Prices, Great Service, Worldwide Brands, Pet Bucket Ltd is a UK registered company | Company no: 08345021 | BTC Bessemer Drive Stevenage | SG1 2DX UK, How to replace dogs’ problem behaviors using differential reinforcement, How to help your dog if he’s afraid of water, Tips to slow down a dog that eats too fast, What to do if your dog hates your new partner, Five tips for walking a fearful or anxious dog. Sometimes your vet will prescribe multiple medications together to both ease your dog’s itchiness and address the root cause of your dog’s skin condition. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. Has anyone had a dermatitis issue as a result of Simparica? She passed away soon after taking this medication. I say yes! I wish I read about this particular product before giving it to my dog because now I'm worried he may get more symptoms. This may post twice - I didn't see my original post so I'm trying again! It is better but not gone. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. Gave my 12 year old labradoodle simpatico just before going to my son’s for T-Day dinner. Treating your pet for active fleas is only part of the process for getting rid of fleas and preventing re-infestation. I’ve spent over $3,000 on vet bills for at least four visits to the ER and follow up lab work including X-rays. When fleas or ticks bite, they are exposed to its FDA-approved ingredient sarolaner, the insecticide, and acaricide that kills parasites fast. I PRAY that our baby is okay with this second dose. The dog is still scratching despite your doing everything right. Today started diarrhea & he has gone 5 times so far while not eating much. Treatment of canine atopic dermatitis: 2010 clinical practice guidelines from the International Task Force on Canine Atopic Dermatitis. Within just three hours, Simparica effectively begins killing fleas and, after 8 hours, starts to kill ticks including the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. Today's Deals; Department. But this month we are at day 7 and I expect the diarrhea it to continue. Wonder why PetSmart offers this if there are so many concerns reported. Back Close × Top Sellers; Dog. I've had to syringe water in his mouth. Gave my dog Charlie Simparica yesterday now he is shaking and panting really bad. All trademarks are the property of Zoetis Services LLC or a related company or a licensor unless otherwise noted.©2021 Zoetis Services LLC. I feel like it was a massive overdose. Today he won’t eat, is sleeping all day, and when he is up he is panting heavily. If you’re noticing an increase in your dog’s scratching, they may have developed one or more of these flare factors that are pushing them over their “itch threshold” despite being on anti-itch medication. Still waiting on the vet and waiting to talk to ASPCA poison control. She had a second one hours later. It also protects against ticks and mites. like she wants me to fix it. Took to vet and she said it could be the Simparico Trio. I’m done with this drug! I am very worried I called the vet they said oops sorry they made a mistake. My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. Dogs treated with SIMPARICA had significantly (p<0.01) fewer live ticks than the controls at 12 hours post-infestation on the same days. Losing my Dolly devastated me and I wanted to warn others about Simparica but I got sick. Gave this to my dogs and now he sleeps all the time and tired and has symptoms now like droopy right side weakness can’t blink right eye and drooling like bell’s palsy. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. Hard fast shaking and terrified eyes. This is still going on weeks later. Thank you all so much!!!! We gave Simparica two days ago and he's not had an appetite, he's eating grass, is drinking a lot of water and sleeping. And it looks like the liver and/or the kidney will not take it too. The Simparica label states that during its 90-day field trial, one of 315 dogs that received the drug "exhibited lethargy, ataxia while posturing to eliminate, elevated third eyelids and inappetence one day after receiving Simparica concurrently with a heartworm preventative (ivermectin/pyrantel pamoate). Thanks all for sharing your experiences. Our dog has not been given another dose. It seemed impossible that our boy could age years in literally 3 days. Took her to her Vet where I was told she had another tremor. We had family in for the weekend and he was not himself. Today is Friday. Thank you in advance. I am currently in the same situation and we are at day 16 after giving simparica. She then joined a multi-specialty referral practice in Rochester, New York where she practiced for 10 years before joining Zoetis. This stuff should be banned. Eight hours later and she has terrible diarrhea and vomiting, now she is not eating. I feel so sad for you Camelia. Didn’t notice anything with first dose. All customers get FREE Shipping on orders over $25 shipped by Amazon. We think that the drug is the cause of the seizures . No appetite, not like Charlie. Today, he wouldn't eat or drink any water. not eating alor and wants me to rub her tummy constantly . It's a great tasting chewable tablet given orally once a month. But what if you’re still seeing your dog itching after they’ve started an anti-itch medication? Today was my 14 year old Jack Russell's 2nd dose of Simparica, her name is Rallye. That is the only thing that has changed in her routine. Last month she had diarrhea and it lasted 7 days. Monday, Tuesday, Wednesday and Thursday he slept all day, was hesitant to get up, wouldn't play with his ball, continued to drink excessively and shivered. However, besides being nervous over the diarrhea, I am petrified about all of these people talking about seizures. Advised her to put a big note on our account that she is never to have this again. Dr. Rosenbaum has lectured extensively and has published articles on a wide variety of dermatology topics. Our dog has had 2 Seizures this month and we are going to stop using Simparica. This time he is having seizures. The reaction lasted less than 12 hours. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick “remedy”… and already several dogs have been adversely affected by this new drug. Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. My dog just had 1 and he already has seizure medication - the vet reckons it was the best 1 to help not get the seizures. These usually occur when your dog has already been scratching an area to the point of inflammation and skin damage, inviting bacteria to multiply and cause an infection. Dr said either Simparica (best case scenario), GOLPP or brain tumor. 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